About us
Our History
Transforming the Understanding and Treatment of Neurodegeneration
ImmunoBrain is a clinical-stage biopharmaceutical company committed to developing innovative immunotherapies for neurological disorders.
1999
Protective Autoimmunity
Prof. Michal Schwartz suggests the concept of “Protective Autoimmunity”,
and that peripheral immune cells play a critical role in shaping brain function.
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1999
2015
ImmunoBrain is founded
ImmunoBrain, Inc. incorporates and enters a Research and License Agreement with Yeda, the commercialization company of the
Weizmann Institute of Science to develop and commercialize the technology
that emerges out of the Schwartz lab.
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2015
2016
Immune checkpoint blockade
First evidence that immune checkpoint therapeutic approach can be utilized
for treating Alzheimer's disease (Baruch et al., 2016, Nature Medicine).
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2016
2017
Lead selection and optimization
ImmunoBrain licenses the rights to develop and commercialize a novel, fully human anti-PD-L1 antibody from Kymab (now a Sanofi company).
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2017
2022
Regulatory approvals
Regulatory approvals received to initiate clinical study in Europe.
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2022
2023
IBC-01-01 clinical study
ImmunoBrain initiates IBC-01-01 Trial, a randomized, double-blind, placebo-controlled, first-in-human Phase Ib clinical trial in persons with early Alzheimer’s disease.
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2023