About us
Our History
Transforming the Understanding and Treatment of Neurodegeneration
ImmunoBrain is a clinical-stage biopharmaceutical company committed to developing innovative immunotherapies for neurological disorders.
1999
Protective Autoimmunity
Prof. Michal Schwartz suggests the concept of “Protective Autoimmunity”,
and that peripheral immune cells play a critical role in shaping brain function.
1999
2015
ImmunoBrain is founded
ImmunoBrain, Inc. incorporates and enters a Research and License Agreement with Yeda, the commercialization company of the
Weizmann Institute of Science to develop and commercialize the technology
that emerges out of the Schwartz lab.
2015
2016
Immune checkpoint blockade
First evidence that immune checkpoint therapeutic approach can be utilized
for treating Alzheimer's disease (Baruch et al., 2016, Nature Medicine).
2016
2017
Lead selection and optimization
ImmunoBrain licenses the rights to develop and commercialize a novel, fully human anti-PD-L1 antibody from Kymab (now a Sanofi company).
2017
2022
Regulatory approvals
Regulatory approvals received to initiate clinical study in Europe.
2022
2023
IBC-01-01 clinical study
ImmunoBrain initiates IBC-01-01 Trial, a randomized, double-blind, placebo-controlled, first-in-human Phase Ib clinical trial in persons with early Alzheimer’s disease.
2023